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KMID : 0358320090500080757
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Korean Journal of Urology
2009 Volume.50 No. 8 p.757 ~ p.761
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Efficacy and Safety of Intravenous Propofol Anesthesia during Transrectal Ultrasound-Guided Prostate Biopsy
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Cha Kyung-Suk
Lee Seung-Wook
Cho Jeong-Man
Kang Jung-Yoon
Yoo Tag-Keun
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Abstract
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Purpose: Transrectal ultrasonography (TRUS)-guided prostate biopsy causes fear and pain in 65% to 90% of patients. This study was designed to evaluated the use of intravenous propofol anesthesia during TRUSguided prostate biopsy.
Materials and Methods: Between January 2006 and June 2008, 195 men undergoing a transrectal prostate biopsy were divided into 2 groups according to anesthetic technique. Group A consisted of 99 patients who received intravenous propofol infusion through an 18 gauge needle during TRUS-guided prostate biopsy. Group B consisted of 96 patients who intrarectally received 10 ml of 2% lidocaine gel 10 minutes before TRUSguided prostate biopsy. Pain scores were assessed on a visual analogue scale immediately after prostate biopsy.
Results: The pain score was significantly reduced in group A compared with group B. There was a significant difference in the mean pain score between the 2 groups (1.0±1.3 in group A versus 2.9±2.0 in group B; p＜ 0.01). Also, there was a significant difference in the willingness to undergo rebiopsy between the 2 groups (83.8% in group A versus 17.7% in group B; p＜0.01). However, the complication rates were not significantly different between the 2 groups. Gross hematuria was found in 14% of group A patients and 18% of group B patients.
Conclusions: Our results proved the advantage of intravenous propofol anesthesia during TRUS-guided prostate biopsy. Intravenous propofol infusion can be a safe and simple technique that significantly reduces pain during TRUS-guided prostate biopsy.
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KEYWORD
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Prostate, Biopsy, Pain, Propofol
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